6USN
Co-crystal structure of SPR with compound 5
Summary for 6USN
Entry DOI | 10.2210/pdb6usn/pdb |
Descriptor | Sepiapterin reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... (7 entities in total) |
Functional Keywords | inhibitor, pain, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 119697.25 |
Authors | |
Primary citation | Gao, H.,Schneider, S.,Andrews, P.,Wang, K.,Huang, X.,Sparling, B.A. Virtual screening to identify potent sepiapterin reductase inhibitors. Bioorg.Med.Chem.Lett., 30:126793-126793, 2020 Cited by PubMed: 31740247DOI: 10.1016/j.bmcl.2019.126793 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.773 Å) |
Structure validation
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