6USN
Co-crystal structure of SPR with compound 5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Sepiapterin reductase | polymer | 263 | 28223.6 | 4 | UniProt (P35270) Pfam (PF00106) | Homo sapiens (Human) | SPR |
| 2 | DA, E, O, W (D, A, B, C) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) | |||
| 3 | EA, F, FA, G, GA... (D, A, B, C) | SULFATE ION | non-polymer | 96.1 | 18 | Chemie (SO4) | |||
| 4 | AA, J, K, L, T (C, A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | BA, M, U (C, A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 6 | CA, LA, N, V (C, D, A, B) | (2-hydroxyphenyl)[3-methyl-1-(pyridin-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl]methanone | non-polymer | 330.3 | 4 | Chemie (QGV) | |||
| 7 | MA, NA, OA, PA (A, B, C, D) | water | water | 18.0 | 174 | Chemie (HOH) |
Sequence modifications
A, B, C, D: -2 - 258 (UniProt: P35270)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 112894.3 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 6802.9 | |
| All* | Total formula weight | 119697.2 |
