6U8C
Crystal structure of an engineered ultra-high affinity Fab-Protein G complex
Summary for 6U8C
Entry DOI | 10.2210/pdb6u8c/pdb |
Descriptor | Protein G, Antibody light chain Fab, Antibody heavy chain Fab, ... (4 entities in total) |
Functional Keywords | engineered fab, protein g, high affinity, immune system |
Biological source | Streptococcus sp. 'group G' More |
Total number of polymer chains | 6 |
Total formula weight | 112044.48 |
Authors | Slezak, T.,Filippova, E.V.,Davydova, E.K.,Kossiakoff, A.A. (deposition date: 2019-09-04, release date: 2019-10-23, Last modification date: 2023-10-11) |
Primary citation | Slezak, T.,Bailey, L.J.,Jaskolowski, M.,Nahotko, D.A.,Filippova, E.V.,Davydova, E.K.,Kossiakoff, A.A. An engineered ultra-high affinity Fab-Protein G pair enables a modular antibody platform with multifunctional capability. Protein Sci., 29:141-156, 2020 Cited by PubMed: 31622515DOI: 10.1002/pro.3751 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.61 Å) |
Structure validation
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