6TYB
Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields
Summary for 6TYB
Entry DOI | 10.2210/pdb6tyb/pdb |
Descriptor | Envelope glycoprotein gp160, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total) |
Functional Keywords | bnabs, gp120, fab, immune system, glycan |
Biological source | Simian immunodeficiency virus (SIV) More |
Total number of polymer chains | 4 |
Total formula weight | 120509.04 |
Authors | Gorman, J.,Kwong, P.D. (deposition date: 2019-08-08, release date: 2019-10-02, Last modification date: 2023-10-11) |
Primary citation | Gorman, J.,Mason, R.D.,Nettey, L.,Cavett, N.,Chuang, G.Y.,Peng, D.,Tsybovsky, Y.,Verardi, R.,Nguyen, R.,Ambrozak, D.,Biris, K.,LaBranche, C.C.,Ramesh, A.,Schramm, C.A.,Zhou, J.,Bailer, R.T.,Kepler, T.B.,Montefiori, D.C.,Shapiro, L.,Douek, D.C.,Mascola, J.R.,Roederer, M.,Kwong, P.D. Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields. Immunity, 51:724-, 2019 Cited by PubMed: 31586542DOI: 10.1016/j.immuni.2019.09.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.301 Å) |
Structure validation
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