6TT3
Crystal structure of 'Res_S2 mutant human Angiotensin-1 converting enzyme N-domain in complex with SG6.
Summary for 6TT3
Entry DOI | 10.2210/pdb6tt3/pdb |
Descriptor | Angiotensin-converting enzyme, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ... (16 entities in total) |
Functional Keywords | angiotensin-1 converting enzyme, ace inhibitor, diprolyl, metalloprotease, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 150705.08 |
Authors | Cozier, G.E.,Acharya, K.R. (deposition date: 2019-12-23, release date: 2020-04-01, Last modification date: 2024-01-24) |
Primary citation | Cozier, G.E.,Lubbe, L.,Sturrock, E.D.,Acharya, K.R. ACE-domain selectivity extends beyond direct interacting residues at the active site. Biochem.J., 477:1241-1259, 2020 Cited by PubMed: 32195541DOI: 10.1042/BCJ20200060 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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