6TR7
N-[2-(5-fluoro-1H-indol-3-yl)ethyl]acetamide-Notum complex
Summary for 6TR7
Entry DOI | 10.2210/pdb6tr7/pdb |
Descriptor | Palmitoleoyl-protein carboxylesterase NOTUM, SULFATE ION, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | wnt receptor frizzled8 carbamazepine, oncoprotein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 45550.04 |
Authors | Zhao, Y.,Jones, E.Y. (deposition date: 2019-12-17, release date: 2020-01-08, Last modification date: 2024-01-24) |
Primary citation | Zhao, Y.,Ren, J.,Hillier, J.,Jones, M.,Lu, W.,Jones, E.Y. Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum. J. Pineal Res., 68:e12630-e12630, 2020 Cited by PubMed: 31876313DOI: 10.1111/jpi.12630 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.47 Å) |
Structure validation
Download full validation report