6T9C
Crystal structure of the complex between PPARgamma LBD and the ligand NV1346 (3a)
Summary for 6T9C
Entry DOI | 10.2210/pdb6t9c/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, 4-hexoxy-~{N}-[(2~{S})-3-methyl-1-(oxidanylamino)-1-oxidanylidene-butan-2-yl]benzamide (3 entities in total) |
Functional Keywords | transcription factor, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 69502.24 |
Authors | Pochetti, G.,Montanari, R.,Capelli, D. (deposition date: 2019-10-27, release date: 2020-02-26, Last modification date: 2024-01-24) |
Primary citation | Montanari, R.,Capelli, D.,Yamamoto, K.,Awaishima, H.,Nishikata, K.,Barendregt, A.,Heck, A.J.R.,Loiodice, F.,Altieri, F.,Paiardini, A.,Grottesi, A.,Pirone, L.,Pedone, E.,Peiretti, F.,Brunel, J.M.,Itoh, T.,Pochetti, G. Insights into PPAR gamma Phosphorylation and Its Inhibition Mechanism. J.Med.Chem., 63:4811-4823, 2020 Cited by PubMed: 32239932DOI: 10.1021/acs.jmedchem.0c00048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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