6T8X
Crystal structure of MAPKAPK2 (MK2) complexed with PF-3644022 and 5-(4-bromophenyl)-N-[4-(1-piperazinyl)phenyl]-N-(2-pyridinylmethyl)-2-furancarboxamide
Summary for 6T8X
Entry DOI | 10.2210/pdb6t8x/pdb |
Descriptor | MAP kinase-activated protein kinase 2, (10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | kinase, non-atp competitive inhibitor, type4, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 6 |
Total formula weight | 226437.52 |
Authors | Beaumont, E.J.,Barker, J. (deposition date: 2019-10-25, release date: 2021-05-12, Last modification date: 2024-01-24) |
Primary citation | Beaumont, E.J.,Barker, J. Crystal structure of MAPKAPK2 (MK2) complexed with PF-3644022 and 5-(4-bromophenyl)-N-[4-(1-piperazinyl)phenyl]-N-(2-pyridinylmethyl)-2-furancarboxamide To Be Published, |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)