6SPI
A4V MUTANT OF HUMAN SOD1 WITH EBSELEN DERIVATIVE 4
Summary for 6SPI
Entry DOI | 10.2210/pdb6spi/pdb |
Descriptor | Superoxide dismutase [Cu-Zn], ~{N}-[(4-chlorophenyl)methyl]-2-selanyl-benzamide, ZINC ION, ... (5 entities in total) |
Functional Keywords | a4v sod1 mutant, ebselen, ebselen derivatives, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 12 |
Total formula weight | 198251.75 |
Authors | Chantadul, V.,Amporndanai, K.,Wright, G.,Antonyuk, S.,Hasnain, S. (deposition date: 2019-09-01, release date: 2020-03-18, Last modification date: 2024-01-24) |
Primary citation | Chantadul, V.,Wright, G.S.A.,Amporndanai, K.,Shahid, M.,Antonyuk, S.V.,Washbourn, G.,Rogers, M.,Roberts, N.,Pye, M.,O'Neill, P.M.,Hasnain, S.S. Ebselen as template for stabilization of A4V mutant dimer for motor neuron disease therapy. Commun Biol, 3:97-97, 2020 Cited by PubMed: 32139772DOI: 10.1038/s42003-020-0826-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report