6S2U
Structure of the catalytic domain of T. thermophilus Rel in complex with AMP and ppGpp
Summary for 6S2U
Entry DOI | 10.2210/pdb6s2u/pdb |
Descriptor | (P)ppGpp synthetase I, SpoT/RelA, MANGANESE (II) ION, ADENOSINE MONOPHOSPHATE, ... (7 entities in total) |
Functional Keywords | ppgpp synthetase, ppgpp hydrolase, ppgpp, translation, stringent response, transferase |
Biological source | Thermus thermophilus |
Total number of polymer chains | 1 |
Total formula weight | 41833.94 |
Authors | Garcia-Pino, A. (deposition date: 2019-06-22, release date: 2020-07-08, Last modification date: 2024-01-24) |
Primary citation | Tamman, H.,Van Nerom, K.,Takada, H.,Vandenberk, N.,Scholl, D.,Polikanov, Y.,Hofkens, J.,Talavera, A.,Hauryliuk, V.,Hendrix, J.,Garcia-Pino, A. A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes. Nat.Chem.Biol., 16:834-840, 2020 Cited by PubMed: 32393900DOI: 10.1038/s41589-020-0520-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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