6S0V

The crystal structure of kanamycin B dioxygenase (KanJ) from Streptomyces kanamyceticus in complex with nickel, neamine and sulfate

Summary for 6S0V

• Entry DOI: 10.2210/pdb6s0v/pdb
• Descriptor: Kanamycin B dioxygenase, NICKEL (II) ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: non-heme iron dioxygenase, alpha-ketoglutarate dioxygenase, kanamycin biosynthesis, kanj, oxidoreductase, metal binding protein
• Biological source: Streptomyces kanamyceticus
• Total number of polymer chains: 6
• Total formula weight: 195062.04

Authors

Mrugala, B.,Niedzialkowska, E.,Minor, W.,Borowski, T. (deposition date: 2019-06-18, release date: 2020-07-08, Last modification date: 2024-01-24)

• Primary citation: Mrugala, B.,Milaczewska, A.,Porebski, P.J.,Niedzialkowska, E.,Guzik, M.,Minor, W.,Borowski, T.; A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates.; Febs J., 288:1366-1386, 2021; PubMed: 32592631; DOI: 10.1111/febs.15462

Experimental method

X-RAY DIFFRACTION (3 Å)