6RT4
The YTH domain of YTHDC1 protein in complex with m6ACU oligonucleotide
Summary for 6RT4
Entry DOI | 10.2210/pdb6rt4/pdb |
Descriptor | RNA (5'-R(*(6MZ)P*C)-3'), YTH domain-containing protein 1, SULFATE ION, ... (4 entities in total) |
Functional Keywords | protein-rna interaction, epitranscriptomics, rna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 40043.28 |
Authors | Bedi, R.,Sledz, P.,Caflisch, A. (deposition date: 2019-05-22, release date: 2019-11-27, Last modification date: 2024-01-24) |
Primary citation | Li, Y.,Bedi, R.K.,Wiedmer, L.,Huang, D.,Sledz, P.,Caflisch, A. Flexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif. J Chem Theory Comput, 15:7004-7014, 2019 Cited by PubMed: 31670957DOI: 10.1021/acs.jctc.9b00987 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.49 Å) |
Structure validation
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