6RB3
Structural basis for recognition and ring-cleavage of the Pseudomonas quinolone signal (PQS) by AqdC variant in complex with its substrate
Summary for 6RB3
Entry DOI | 10.2210/pdb6rb3/pdb |
Descriptor | Putative dioxygenase (1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase), 2-heptylquinoline-3,4-diol (3 entities in total) |
Functional Keywords | dioxygenase; alpha/beta hydrolase fold, catalytic triad, quorum sensing, pseudomonas quinolone signal, pseudomonas aeruginosa, hydrolase |
Biological source | Mycobacterium abscessus |
Total number of polymer chains | 3 |
Total formula weight | 90017.93 |
Authors | Wullich, S.,Kobus, S.,Smits, S.H.,Fetzner, S. (deposition date: 2019-04-09, release date: 2019-07-03, Last modification date: 2024-01-24) |
Primary citation | Wullich, S.C.,Kobus, S.,Wienhold, M.,Hennecke, U.,Smits, S.H.J.,Fetzner, S. Structural basis for recognition and ring-cleavage of the Pseudomonas quinolone signal (PQS) by AqdC, a mycobacterial dioxygenase of the alpha / beta-hydrolase fold family. J.Struct.Biol., 207:287-294, 2019 Cited by PubMed: 31228546DOI: 10.1016/j.jsb.2019.06.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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