6RB3
Structural basis for recognition and ring-cleavage of the Pseudomonas quinolone signal (PQS) by AqdC variant in complex with its substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (E, A, B) | Putative dioxygenase (1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase) | polymer | 269 | 29746.6 | 3 | UniProt (B1MFK2) Pfam (PF00561) | Mycobacterium abscessus | |
| 2 | D, E, F (E, A, B) | 2-heptylquinoline-3,4-diol | non-polymer | 259.3 | 3 | Chemie (JWW) | |||
| 3 | G, H, I (E, A, B) | water | water | 18.0 | 448 | Chemie (HOH) |
Sequence modifications
E, A, B: -1 - 267 (UniProt: B1MFK2)
| PDB | External Database | Details |
|---|---|---|
| Ser 94 | Ala 96 | engineered mutation |
| Ala 244 | His 246 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 89239.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 778.0 | |
| All* | Total formula weight | 90017.9 |
