6QTK
2.31A structure of gepotidacin with S.aureus DNA gyrase and doubly nicked DNA
Summary for 6QTK
Entry DOI | 10.2210/pdb6qtk/pdb |
Descriptor | DNA gyrase subunit B, DNA gyrase subunit A, DNA (5'-D(*AP*GP*CP*CP*GP*TP*AP*G*GP*GP*TP*AP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), ... (8 entities in total) |
Functional Keywords | inhibitor, dna, complex, isomerase |
Biological source | Staphylococcus aureus (strain N315) More |
Total number of polymer chains | 6 |
Total formula weight | 169842.07 |
Authors | Bax, B.D. (deposition date: 2019-02-25, release date: 2019-03-13, Last modification date: 2024-01-24) |
Primary citation | Gibson, E.G.,Bax, B.,Chan, P.F.,Osheroff, N. Mechanistic and Structural Basis for the Actions of the Antibacterial Gepotidacin against Staphylococcus aureus Gyrase. Acs Infect Dis., 5:570-581, 2019 Cited by PubMed: 30757898DOI: 10.1021/acsinfecdis.8b00315 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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