6PKU
Guinea pig N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA) catalytic domain (C51S C221S) in complex with N-acetyl-alpha-D-glucosamine (alpha-GlcNAc) and mannose 6-phosphate (M6P)
Summary for 6PKU
Entry DOI | 10.2210/pdb6pku/pdb |
Descriptor | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA), 2-acetamido-2-deoxy-alpha-D-glucopyranose, 6-O-phosphono-alpha-D-mannopyranose, ... (5 entities in total) |
Functional Keywords | uncovering enzyme, mannose 6-phosphate, glycosidase, n-acetylglucosamine, hydrolase |
Biological source | Cavia porcellus (Guinea pig) |
Total number of polymer chains | 4 |
Total formula weight | 132119.09 |
Authors | Gorelik, A.,Illes, K.,Nagar, B. (deposition date: 2019-06-29, release date: 2020-02-19, Last modification date: 2023-10-11) |
Primary citation | Gorelik, A.,Illes, K.,Nagar, B. Crystal Structure of the Mannose-6-Phosphate Uncovering Enzyme. Structure, 28:426-436.e3, 2020 Cited by PubMed: 32109365DOI: 10.1016/j.str.2020.02.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.949 Å) |
Structure validation
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