6P3O
Tetrahydroprotoberberine N-methyltransferase in complex with (S)-cis-N-methylstylopine and S-adenosylhomocysteine
Summary for 6P3O
Entry DOI | 10.2210/pdb6p3o/pdb |
Descriptor | Tetrahydroprotoberberine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, (5S,12bS)-5-methyl-6,7,12b,13-tetrahydro-2H,4H,10H-[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquinolino[3,2-a]isoquinolin-5-ium, ... (4 entities in total) |
Functional Keywords | methyltransferase, transferase |
Biological source | Glaucium flavum |
Total number of polymer chains | 1 |
Total formula weight | 44524.71 |
Authors | Lang, D.E.,Morris, J.S.,Rowley, M.,Torres, M.A.,Maksimovich, V.A.,Facchini, P.J.,Ng, K.K.S. (deposition date: 2019-05-24, release date: 2019-08-14, Last modification date: 2023-10-11) |
Primary citation | Lang, D.E.,Morris, J.S.,Rowley, M.,Torres, M.A.,Maksimovich, V.A.,Facchini, P.J.,Ng, K.K.S. Structure-function studies of tetrahydroprotoberberineN-methyltransferase reveal the molecular basis of stereoselective substrate recognition. J.Biol.Chem., 294:14482-14498, 2019 Cited by PubMed: 31395658DOI: 10.1074/jbc.RA119.009214 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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