6OYH
Crystal structure of MraY bound to carbacaprazamycin
Summary for 6OYH
Entry DOI | 10.2210/pdb6oyh/pdb |
Descriptor | MraYAA nanobody, Phospho-N-acetylmuramoyl-pentapeptide-transferase, (5S)-5'-O-(5-amino-5-deoxy-beta-D-ribofuranosyl)-5'-C-[(2S,5S,6S)-5-carboxy-6-heptadecyl-1,4-dimethyl-3-oxo-1,4-diazepan-2-yl]uridine, ... (4 entities in total) |
Functional Keywords | peptidoglycan biosynthesis, antibiotic target, integral membrane enzyme, translocase, membrane protein, membrane protein-transferase complex, membrane protein/transferase |
Biological source | Lama glama (llama) More |
Total number of polymer chains | 8 |
Total formula weight | 227241.24 |
Authors | Mashalidis, E.H.,Lee, S.Y. (deposition date: 2019-05-14, release date: 2019-07-10, Last modification date: 2023-10-11) |
Primary citation | Mashalidis, E.H.,Kaeser, B.,Terasawa, Y.,Katsuyama, A.,Kwon, D.Y.,Lee, K.,Hong, J.,Ichikawa, S.,Lee, S.Y. Chemical logic of MraY inhibition by antibacterial nucleoside natural products. Nat Commun, 10:2917-2917, 2019 Cited by PubMed: 31266949DOI: 10.1038/s41467-019-10957-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
Download full validation report