6O9E
Structure of HIV-1 Reverse Transcriptase in complex with DNA and INDOPY-1
Summary for 6O9E
Entry DOI | 10.2210/pdb6o9e/pdb |
Related PRD ID | PRD_900003 |
Descriptor | Reverse transcriptase p66, TETRAETHYLENE GLYCOL, Reverse transcriptase p51, ... (11 entities in total) |
Functional Keywords | human immunodeficiency virus 1, protein/dna, nucleotide-competing reverse transcriptase inhibitor, transferase, transferase-dna complex, transferase/dna |
Biological source | Human immunodeficiency virus type 1 (HIV-1) More |
Total number of polymer chains | 6 |
Total formula weight | 254104.87 |
Authors | Ruiz, F.X.,Hoang, A.,Das, K.,Arnold, E. (deposition date: 2019-03-13, release date: 2019-10-23, Last modification date: 2023-10-11) |
Primary citation | Ruiz, F.X.,Hoang, A.,Das, K.,Arnold, E. Structural Basis of HIV-1 Inhibition by Nucleotide-Competing Reverse Transcriptase Inhibitor INDOPY-1. J.Med.Chem., 62:9996-10002, 2019 Cited by PubMed: 31603676DOI: 10.1021/acs.jmedchem.9b01289 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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