6NTK
Crystal Structure of Recombinant Human Acetylcholinesterase Inhibited by A-232
Summary for 6NTK
Entry DOI | 10.2210/pdb6ntk/pdb |
Related | 6NTG 6NTH |
Descriptor | Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | hydrolase, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 121289.71 |
Authors | Bester, S.M.,Guelta, M.A.,Height, J.J.,Pegan, S.D. (deposition date: 2019-01-29, release date: 2020-07-01, Last modification date: 2023-10-11) |
Primary citation | Height, J.J.,Bester, S.M.,Guelta, M.A.,Bae, S.Y.,Cheung, J.,Pegan, S.D. Insights into inhibition of human acetylcholinesterase by Novichok, A-series Nerve Agents To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.406 Å) |
Structure validation
Download full validation report