6NC3

AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody VRC34 fragment antigen binding

This is a non-PDB format compatible entry.

Summary for 6NC3

• Entry DOI: 10.2210/pdb6nc3/pdb
• EMDB information: 0434
• Descriptor: HIV-1 Env AMC011 v4.2 SOSIP gp120, HIV-1 Env AMC011 v4.2 SOSIP gp41, Monoclonal antibody VRC34.01 fragment antigen binding heavy chain, ... (9 entities in total)
• Functional Keywords: hiv-1 env, sosip, trimer, broadly neutralizing antibody, fusion peptide, viral protein, immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 24
• Total formula weight: 760646.34

Authors

Cottrell, C.A.,Ozorowski, G.,Torres, J.L.,Ward, A.B. (deposition date: 2018-12-10, release date: 2019-06-19, Last modification date: 2020-07-29)

• Primary citation: Yuan, M.,Cottrell, C.A.,Ozorowski, G.,van Gils, M.J.,Kumar, S.,Wu, N.C.,Sarkar, A.,Torres, J.L.,de Val, N.,Copps, J.,Moore, J.P.,Sanders, R.W.,Ward, A.B.,Wilson, I.A.; Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies.; Cell Host Microbe, 25:873-, 2019; PubMed: 31194940; DOI: 10.1016/j.chom.2019.04.011

Experimental method

ELECTRON MICROSCOPY (4.5 Å)