6NC3

AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody VRC34 fragment antigen binding

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, D, E, F...	HIV-1 Env AMC011 v4.2 SOSIP gp120	polymer	512	57668.9	6		Human immunodeficiency virus 1
2	B, I, J, K, M...	HIV-1 Env AMC011 v4.2 SOSIP gp41	polymer	153	17300.7	6	Pfam (PF00517) UniProt (by SIFTS) (Q78156) In PDB	Human immunodeficiency virus 1
3	H, O, P, Q, R...	Monoclonal antibody VRC34.01 fragment antigen binding heavy chain	polymer	222	23668.4	6		Homo sapiens (human)
4	L, T, U, V, W...	Monoclonal antibody VRC34.01 fragment antigen binding light chain	polymer	210	22880.5	6		Homo sapiens (human)
5	0, b, 3, f, 7...	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	12	In PDB GlyTouCan (G22768VO)
6	1, c, 4, g, 8...	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	12	In PDB GlyTouCan (G42666HT)
7	a, 2, h, 9, o...	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	6	In PDB GlyTouCan (G22573RC)
8	d, e, 5, 6, k...	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	12	In PDB GlyTouCan (G15407YE)
9	F, G, A, C, D...	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	18	Chemie (NAG)

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	729111.3
Branched	Number of molecules	42
	Total formula weight	27553.3
Non-Polymers*	Number of molecules	18
	Total formula weight	3981.7
All*	Total formula weight	760646.3

*Water molecules are not included.