Summary for 6MXT
Entry DOI | 10.2210/pdb6mxt/pdb |
Descriptor | Endolysin, Beta-2 adrenergic receptor chimera, nanobody Nb71, salmeterol, ... (10 entities in total) |
Functional Keywords | g protein-coupled receptor, adrenergic receptor, asthma drug, active conformation, nanobody, signaling protein-hormone complex, membrane protein, signaling protein/hormone |
Biological source | Enterobacteria phage T4 More |
Total number of polymer chains | 2 |
Total formula weight | 68731.36 |
Authors | Masureel, M.,Zou, Y.,Picard, L.P.,van der Westhuizen, E.,Mahoney, J.P.,Rodrigues, J.P.G.L.M.,Mildorf, T.J.,Dror, R.O.,Shaw, D.E.,Bouvier, M.,Pardon, E.,Steyaert, J.,Sunahara, R.K.,Weis, W.I.,Zhang, C.,Kobilka, B.K. (deposition date: 2018-10-31, release date: 2018-11-14, Last modification date: 2023-10-11) |
Primary citation | Masureel, M.,Zou, Y.,Picard, L.P.,van der Westhuizen, E.,Mahoney, J.P.,Rodrigues, J.P.G.L.M.,Mildorf, T.J.,Dror, R.O.,Shaw, D.E.,Bouvier, M.,Pardon, E.,Steyaert, J.,Sunahara, R.K.,Weis, W.I.,Zhang, C.,Kobilka, B.K. Structural insights into binding specificity, efficacy and bias of a beta2AR partial agonist. Nat. Chem. Biol., 14:1059-1066, 2018 Cited by PubMed: 30327561DOI: 10.1038/s41589-018-0145-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95934213525 Å) |
Structure validation
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