6M9T
Crystal structure of EP3 receptor bound to misoprostol-FA
Summary for 6M9T
Entry DOI | 10.2210/pdb6m9t/pdb |
Descriptor | Prostaglandin E2 receptor EP3 subtype, Endolysin chimera, (11alpha,12alpha,13E,16S)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid, SULFATE ION, ... (6 entities in total) |
Functional Keywords | gpcr, prostaglandin e2 receptor 3 (ep3), prostaglandin analogue, membrane protein, misoprostol-fa (biologically active free acid), xfel, lcp, t4l |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 62262.59 |
Authors | Audet, M.,White, K.L.,Breton, B.,Zarzycka, B.,Han, G.W.,Lu, Y.,Gati, C.,Batyuk, A.,Popov, P.,Velasquez, J.,Manahan, D.,Hu, H.,Weierstall, U.,Liu, W.,Shui, W.,Katrich, V.,Cherezov, V.,Hanson, M.A.,Stevens, R.C. (deposition date: 2018-08-24, release date: 2018-12-05, Last modification date: 2023-10-11) |
Primary citation | Audet, M.,White, K.L.,Breton, B.,Zarzycka, B.,Han, G.W.,Lu, Y.,Gati, C.,Batyuk, A.,Popov, P.,Velasquez, J.,Manahan, D.,Hu, H.,Weierstall, U.,Liu, W.,Shui, W.,Katritch, V.,Cherezov, V.,Hanson, M.A.,Stevens, R.C. Crystal structure of misoprostol bound to the labor inducer prostaglandin E2receptor. Nat. Chem. Biol., 15:11-17, 2019 Cited by PubMed: 30510194DOI: 10.1038/s41589-018-0160-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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