6M9H

JAK2 JH2 in complex with diaminopyrimidine JAK040

Summary for 6M9H

• Entry DOI: 10.2210/pdb6m9h/pdb
• Descriptor: Tyrosine-protein kinase JAK2, 4-({4-amino-6-[4-(2-hydroxyethyl)-1H-imidazol-1-yl]pyrimidin-2-yl}amino)benzonitrile, GLYCEROL, ... (5 entities in total)
• Functional Keywords: transferase/transferase inhibitor, transferase, transferase-transferase inhibitor complex
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 33612.53

Authors

Puleo, D.E.,Schlessinger, J.,Jorgensen, W.L. (deposition date: 2018-08-23, release date: 2018-09-05, Last modification date: 2024-03-13)

• Primary citation: Puleo, D.E.,Schlessinger, J.; JAK2 JH2 Binders; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.79 Å)