6M47
X-ray structure of a Drosophila dopamine transporter with NET-like mutations (D121G/S426M/F471L) in tramadol bound form
Summary for 6M47
Entry DOI | 10.2210/pdb6m47/pdb |
Related | 6M0F 6M0Z 6M2R 6M38 6M3Z |
Related PRD ID | PRD_900001 |
Descriptor | Sodium-dependent dopamine transporter, DECANE, Antibody fragment 9D5 light chain, ... (11 entities in total) |
Functional Keywords | neurotransmitter transporter, antibody fragment, membrane protein |
Biological source | Drosophila melanogaster (Fruit fly) More |
Total number of polymer chains | 3 |
Total formula weight | 108815.43 |
Authors | Shabareesh, P.,Mallela, A.K.,Joseph, D.,Penmatsa, A. (deposition date: 2020-03-05, release date: 2021-02-17, Last modification date: 2023-11-29) |
Primary citation | Pidathala, S.,Mallela, A.K.,Joseph, D.,Penmatsa, A. Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12:2199-2199, 2021 Cited by PubMed: 33850134DOI: 10.1038/s41467-021-22385-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.252 Å) |
Structure validation
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