6LQ9
S109 in complex with CRM1-Ran-RanBP1
Summary for 6LQ9
Entry DOI | 10.2210/pdb6lq9/pdb |
Descriptor | GTP-binding nuclear protein Ran, Ran-specific GTPase-activating protein 1, Exportin-1, ... (10 entities in total) |
Functional Keywords | transport protein, nuclear export, complex, mutant, activation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 161767.70 |
Authors | |
Primary citation | Lei, Y.,An, Q.,Shen, X.F.,Sui, M.,Li, C.,Jia, D.,Luo, Y.,Sun, Q. Structure-Guided Design of the First Noncovalent Small-Molecule Inhibitor of CRM1. J.Med.Chem., 64:6596-6607, 2021 Cited by PubMed: 33974430DOI: 10.1021/acs.jmedchem.0c01675 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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