6KX1
Crystal structure of SN-101 mAb in complex with MUC1 glycopeptide
Summary for 6KX1
Entry DOI | 10.2210/pdb6kx1/pdb |
Descriptor | Fab Fragment-SN-101-Heavy chain, Fab Fragment-SN-101-Light chain, Synthetic MUC1 glycopepide, ... (5 entities in total) |
Functional Keywords | antibody, igg1, muc1, glycopeptide, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 3 |
Total formula weight | 53656.21 |
Authors | Wakui, H.,Tanaka, Y.,Kato, K.,Ose, T.,Matsumoto, I.,Min, Y.,Tachibana, T.,Nishimura, S.-I. (deposition date: 2019-09-09, release date: 2020-07-29, Last modification date: 2023-11-22) |
Primary citation | Wakui, H.,Tanaka, Y.,Ose, T.,Matsumoto, I.,Kato, K.,Min, Y.,Tachibana, T.,Sato, M.,Naruchi, K.,Martin, F.G.,Hinou, H.,Nishimura, S.-I. A straightforward approach to antibodies recognising cancer specific glycopeptidic neoepitopes Chem Sci, 11:4999-5006, 2020 Cited by DOI: 10.1039/D0SC00317DPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.773 Å) |
Structure validation
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