6KVP
S. aureus FtsZ in complex with 3-(1-(5-bromo-4-(4-(trifluoromethyl)phenyl)oxazol-2-yl)ethoxy)-2,6-difluorobenzamide (compound 2)
Summary for 6KVP
Entry DOI | 10.2210/pdb6kvp/pdb |
Descriptor | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | gtpase, protein-inhibitor complex, hydrolase |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 1 |
Total formula weight | 32827.51 |
Authors | Ferrer-Gonzalez, E.,Fujita, J.,Yoshizawa, T.,Nelson, J.M.,Pilch, A.J.,Hillman, E.,Ozawa, M.,Kuroda, N.,Parhi, A.K.,LaVoie, E.J.,Matsumura, H.,Pilch, D.S. (deposition date: 2019-09-05, release date: 2020-01-15, Last modification date: 2023-11-22) |
Primary citation | Ferrer-Gonzalez, E.,Fujita, J.,Yoshizawa, T.,Nelson, J.M.,Pilch, A.J.,Hillman, E.,Ozawa, M.,Kuroda, N.,Al-Tameemi, H.M.,Boyd, J.M.,LaVoie, E.J.,Matsumura, H.,Pilch, D.S. Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens. Sci Rep, 9:20092-20092, 2019 Cited by PubMed: 31882782DOI: 10.1038/s41598-019-56557-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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