6K9M
Human LXR-beta in complex with an agonist
Summary for 6K9M
Entry DOI | 10.2210/pdb6k9m/pdb |
Descriptor | Oxysterols receptor LXR-beta, ~{tert}-butyl (2'~{S},3~{S})-2-oxidanylidene-2'-propan-2-yl-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate (3 entities in total) |
Functional Keywords | nuclear receptor, dna binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 126008.04 |
Authors | |
Primary citation | Chen, Z.,Chen, H.,Zhang, Z.,Ding, P.,Yan, X.,Li, Y.,Zhang, S.,Gu, Q.,Zhou, H.,Xu, J. Discovery of novel liver X receptor inverse agonists as lipogenesis inhibitors. Eur.J.Med.Chem., 206:112793-112793, 2020 Cited by PubMed: 32961480DOI: 10.1016/j.ejmech.2020.112793 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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