6K4D

Ancestral luciferase AncLamp in complex with ATP and D-luciferin

Summary for 6K4D

Entry DOI	10.2210/pdb6k4d/pdb
Descriptor	Ancestral luciferase AncLamp, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] (4S)-2-(6-oxidanyl-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylate, (4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid, ... (4 entities in total)
Functional Keywords	luciferase, bioluminescence, ancestral protein, molecular evolution, oxidoreductase
Biological source	Lampyridae
Total number of polymer chains	1
Total formula weight	61264.22
Authors	Oba, Y.,Konishi, K.,Yano, D.,Kato, D.,Shirai, T. (deposition date: 2019-05-23, release date: 2020-05-27, Last modification date: 2023-11-22)
Primary citation	Oba, Y.,Konishi, K.,Yano, D.,Shibata, H.,Kato, D.,Shirai, T. Resurrecting the ancient glow of the fireflies. Sci Adv, 6:-, 2020 Cited by PubMed: 33268373 DOI: 10.1126/sciadv.abc5705 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation