6JPW
Crystal structure of Zika NS2B-NS3 protease with compound 1C
Summary for 6JPW
Entry DOI | 10.2210/pdb6jpw/pdb |
Descriptor | Serine protease subunit NS2B, NS3 protease, SER-C0F-GLY-LYS-ARG-LYS, ... (4 entities in total) |
Functional Keywords | viral protease, protease inhibitor complex, viral protein |
Biological source | Zika virus (ZIKV) More |
Total number of polymer chains | 11 |
Total formula weight | 102173.94 |
Authors | Quek, J.P. (deposition date: 2019-03-28, release date: 2019-06-26, Last modification date: 2023-11-22) |
Primary citation | Nitsche, C.,Onagi, H.,Quek, J.P.,Otting, G.,Luo, D.,Huber, T. Biocompatible Macrocyclization between Cysteine and 2-Cyanopyridine Generates Stable Peptide Inhibitors. Org.Lett., 21:4709-4712, 2019 Cited by PubMed: 31188009DOI: 10.1021/acs.orglett.9b01545 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.951 Å) |
Structure validation
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