6JPW
Crystal structure of Zika NS2B-NS3 protease with compound 1C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Serine protease subunit NS2B | polymer | 53 | 5865.4 | 4 | UniProt (Q32ZE1) Pfam (PF01002) | Zika virus (ZIKV) | NS2B cofactor |
| 2 | B, D, F, H (B, D, F, H) | NS3 protease | polymer | 178 | 19037.6 | 4 | UniProt (A0A142IX72) Pfam (PF00949) UniProt (by SIFTS) (Q32ZE1) | Zika virus (strain Mr 766) (ZIKV) | |
| 3 | I, J, K (J, K, L) | SER-C0F-GLY-LYS-ARG-LYS | polymer | 6 | 854.0 | 3 | synthetic construct | ||
| 4 | L, M, N, O, P... (A, B, C, D, E...) | water | water | 18.0 | 303 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 46 - 96 (UniProt: Q32ZE1)
B, D, F, H: 1 - 177 (UniProt: A0A142IX72)
| PDB | External Database | Details |
|---|---|---|
| Met 44 | - | initiating methionine |
| Thr 45 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 102173.9 | |
| All* | Total formula weight | 102173.9 |
