6J1N
Anisodus acutangulus type III polyketide sythase AaPKS2 in complex with 4-carboxy-3-oxobutanoyl-CoA
Summary for 6J1N
| Entry DOI | 10.2210/pdb6j1n/pdb |
| Descriptor | A. acutangulus PKS2, (3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,19,21-tetraoxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide (non-preferred name) (3 entities in total) |
| Functional Keywords | anisodus acutangulus, type iii polyketide sythase, tropane alkaloids biosynthesis, biosynthetic protein |
| Biological source | Anisodus acutangulus |
| Total number of polymer chains | 2 |
| Total formula weight | 95244.94 |
| Authors | Fang, C.L.,Zhang, Y. (deposition date: 2018-12-28, release date: 2019-09-11, Last modification date: 2023-11-22) |
| Primary citation | Huang, J.P.,Fang, C.,Ma, X.,Wang, L.,Yang, J.,Luo, J.,Yan, Y.,Zhang, Y.,Huang, S.X. Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation. Nat Commun, 10:4036-4036, 2019 Cited by PubMed: 31492848DOI: 10.1038/s41467-019-11987-z PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.532 Å) |
Structure validation
Download full validation report
