6IX5
The structure of LepI complex with SAM and its substrate analogue
Summary for 6IX5
Entry DOI | 10.2210/pdb6ix5/pdb |
Descriptor | O-methyltransferase lepI, S-ADENOSYLMETHIONINE, 4-hydroxy-3-[(2S,6E,8E)-2-methyldeca-6,8-dienoyl]-5-phenylpyridin-2(1H)-one, ... (9 entities in total) |
Functional Keywords | leporin, sam, o-methyltransferase, pericyclase, biosynthetic protein |
Biological source | Aspergillus flavus |
Total number of polymer chains | 2 |
Total formula weight | 93967.00 |
Authors | Cai, Y.,Ohashi, M.,Hai, Y.,Tang, Y.,Zhou, J. (deposition date: 2018-12-09, release date: 2019-07-17, Last modification date: 2023-11-22) |
Primary citation | Cai, Y.,Hai, Y.,Ohashi, M.,Jamieson, C.S.,Garcia-Borras, M.,Houk, K.N.,Zhou, J.,Tang, Y. Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI. Nat.Chem., 11:812-820, 2019 Cited by PubMed: 31332284DOI: 10.1038/s41557-019-0294-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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