6IQL

Crystal structure of dopamine receptor D4 bound to the subtype-selective ligand, L745870

Summary for 6IQL

Entry DOI	10.2210/pdb6iql/pdb
Descriptor	D(4) dopamine receptor,Soluble cytochrome b562,D(4) dopamine receptor, 3-{[4-(4-chlorophenyl)piperazin-1-yl]methyl}-1H-pyrrolo[2,3-b]pyridine (2 entities in total)
Functional Keywords	gpcr, drd4, l745870, ligand, dimerization, signaling protein
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	2
Total formula weight	87785.01
Authors	Zhou, Y.,Cao, C.,Zhang, X.C. (deposition date: 2018-11-08, release date: 2019-12-04, Last modification date: 2023-11-22)
Primary citation	Zhou, Y.,Cao, C.,He, L.,Wang, X.,Zhang, X.C. Crystal structure of dopamine receptor D4 bound to the subtype selective ligand, L745870. Elife, 8:-, 2019 Cited by PubMed: 31750832 DOI: 10.7554/eLife.48822 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation