6IAM
Modulating Protein-Protein Interactions with Visible Light Peptide Backbone Switches
Summary for 6IAM
Entry DOI | 10.2210/pdb6iam/pdb |
Descriptor | WD repeat-containing protein 5, SER-ALA-ARG-ALA-XY5-VAL-HIS-LEU-ARG-LYS-SER-ALA, Small ubiquitin-related modifier 5, ... (6 entities in total) |
Functional Keywords | histone modification, trimethylation at 'lys-4', epigenetic transcriptional activation, nsl complex, osteoblasts differentiation, leukemia, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 35775.73 |
Authors | Werel, L.,Essen, L.-O. (deposition date: 2018-11-27, release date: 2019-02-06, Last modification date: 2024-07-10) |
Primary citation | Albert, L.,Penalver, A.,Djokovic, N.,Werel, L.,Hoffarth, M.,Ruzic, D.,Xu, J.,Essen, L.O.,Nikolic, K.,Dou, Y.,Vazquez, O. Modulating Protein-Protein Interactions with Visible-Light-Responsive Peptide Backbone Photoswitches. Chembiochem, 20:1417-1429, 2019 Cited by PubMed: 30675988DOI: 10.1002/cbic.201800737 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.51 Å) |
Structure validation
Download full validation report