6I6F
SEPIAPTERIN REDUCTASE IN COMPLEX WITH COMPOUND 1
Summary for 6I6F
Entry DOI | 10.2210/pdb6i6f/pdb |
Descriptor | Sepiapterin reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ethyl 4-azanyl-3-bromanyl-benzoate, ... (5 entities in total) |
Functional Keywords | sepiapterin-reductase, oxidoreductase, proteros biostructures gmbh |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 62434.71 |
Authors | Alen, J.,Schade, M.,Wagener, M.,Blaesse, M. (deposition date: 2018-11-15, release date: 2019-07-10, Last modification date: 2024-05-15) |
Primary citation | Alen, J.,Schade, M.,Wagener, M.,Christian, F.,Nordhoff, S.,Merla, B.,Dunkern, T.R.,Bahrenberg, G.,Ratcliffe, P. Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors. J.Med.Chem., 62:6391-6397, 2019 Cited by PubMed: 31244106DOI: 10.1021/acs.jmedchem.9b00218 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.94 Å) |
Structure validation
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