6I2F
Human Carbonic Anhydrase II in complex with 4-Propoxybenzenesulfonamide
Summary for 6I2F
Entry DOI | 10.2210/pdb6i2f/pdb |
Related | 6GDC 6GM9 6HQX 6HR3 6HXD 6I0W 6I1U |
Descriptor | Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (7 entities in total) |
Functional Keywords | lyase, inhibitor, complex, co2 conversion |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 30990.31 |
Authors | Gloeckner, S.,Heine, A.,Klebe, G. (deposition date: 2018-11-01, release date: 2019-11-20, Last modification date: 2024-01-24) |
Primary citation | Glockner, S.,Ngo, K.,Sager, C.P.,Hufner-Wulsdorf, T.,Heine, A.,Klebe, G. Conformational Changes in Alkyl Chains Determine the Thermodynamic and Kinetic Binding Profiles of Carbonic Anhydrase Inhibitors. Acs Chem.Biol., 15:675-685, 2020 Cited by PubMed: 32027480DOI: 10.1021/acschembio.9b00895 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.198 Å) |
Structure validation
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