6HY7
Crystal structure of alpha9 nAChR extracellular domain in complex with alpha-conotoxin RgIA
Summary for 6HY7
Entry DOI | 10.2210/pdb6hy7/pdb |
Descriptor | Neuronal acetylcholine receptor subunit alpha-9, Alpha-conotoxin RgIA, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | alpha9, ion channel, nachr, acetylcholine, conotoxin, rgia, antagonist, toxin |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 27389.40 |
Authors | Giastas, P.,Zouridakis, M. (deposition date: 2018-10-19, release date: 2019-05-22, Last modification date: 2024-01-24) |
Primary citation | Zouridakis, M.,Papakyriakou, A.,Ivanov, I.A.,Kasheverov, I.E.,Tsetlin, V.,Tzartos, S.,Giastas, P. Crystal Structure of the Monomeric Extracellular Domain of alpha 9 Nicotinic Receptor Subunit in Complex With alpha-Conotoxin RgIA: Molecular Dynamics Insights Into RgIA Binding to alpha 9 alpha 10 Nicotinic Receptors. Front Pharmacol, 10:474-474, 2019 Cited by PubMed: 31118896DOI: 10.3389/fphar.2019.00474 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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