6HAK
Crystal structure of HIV-1 reverse transcriptase (RT) in complex with a double stranded RNA represents the RT transcription initiation complex prior to nucleotide incorporation
Summary for 6HAK
Entry DOI | 10.2210/pdb6hak/pdb |
Related PRD ID | PRD_900003 |
Descriptor | Gag-Pol polyprotein, RNA (5'-R(P*AP*GP*UP*GP*GP*CP*GP*GP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*C)-3'), RNA (5'-R(P*UP*CP*CP*CP*UP*GP*UP*UP*CP*GP*GP*CP*CP*GP*CP*CP*A)-3'), ... (7 entities in total) |
Functional Keywords | trna-lys3, protein-rna cross-link, transcription initiation, viral rna, dna polymerase, transcription |
Biological source | Human immunodeficiency virus type 1 BH10 More |
Total number of polymer chains | 8 |
Total formula weight | 257970.25 |
Authors | Das, K.,Martinez, S.E.,Arnold, E. (deposition date: 2018-08-07, release date: 2019-04-03, Last modification date: 2024-01-17) |
Primary citation | Das, K.,Martinez, S.E.,DeStefano, J.J.,Arnold, E. Structure of HIV-1 RT/dsRNA initiation complex prior to nucleotide incorporation. Proc.Natl.Acad.Sci.USA, 116:7308-7313, 2019 Cited by PubMed: 30902895DOI: 10.1073/pnas.1814170116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.95 Å) |
Structure validation
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