6H7Z
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a inhibitor RNA 2-65-1
Summary for 6H7Z
Entry DOI | 10.2210/pdb6h7z/pdb |
Descriptor | Glutamate carboxypeptidase 2, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (13 entities in total) |
Functional Keywords | glutamate carboxypeptidase ii (gcpii); naaladase; prostate-specific membrane antigen; urea based inhibitor, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 84492.58 |
Authors | Motlova, L.,Novakova, Z.,Barinka, C. (deposition date: 2018-07-31, release date: 2018-12-05, Last modification date: 2024-01-17) |
Primary citation | Nakajima, R.,Novakova, Z.,Tueckmantel, W.,Motlova, L.,Barinka, C.,Kozikowski, A.P. 2-Aminoadipic Acid-C(O)-Glutamate Based Prostate-Specific Membrane Antigen Ligands for Potential Use as Theranostics. ACS Med Chem Lett, 9:1099-1104, 2018 Cited by PubMed: 30429952DOI: 10.1021/acsmedchemlett.8b00318 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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