6H5R
Structure of the complex of a human telomeric DNA with bis(1-butyl-3-methyl-imidazole-2-ylidene) gold(I)
Summary for 6H5R
Entry DOI | 10.2210/pdb6h5r/pdb |
Descriptor | Human Telomeric DNA, POTASSIUM ION, STRONTIUM ION, ... (5 entities in total) |
Functional Keywords | drug-dna complex, g quadruplex, dna |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 9651.25 |
Authors | Bazzicalupi, C.,Gratteri, P.,Papi, F. (deposition date: 2018-07-25, release date: 2019-01-30, Last modification date: 2024-01-17) |
Primary citation | Guarra, F.,Marzo, T.,Ferraroni, M.,Papi, F.,Bazzicalupi, C.,Gratteri, P.,Pescitelli, G.,Messori, L.,Biver, T.,Gabbiani, C. Interaction of a gold(i) dicarbene anticancer drug with human telomeric DNA G-quadruplex: solution and computationally aided X-ray diffraction analysis. Dalton Trans, 47:16132-16138, 2018 Cited by PubMed: 30378627DOI: 10.1039/c8dt03607a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report