6H15
Structure of LRP6 P3E3P4E4 in complex with VHH L-P2-B10
Summary for 6H15
Entry DOI | 10.2210/pdb6h15/pdb |
Descriptor | Low-density lipoprotein receptor-related protein 6, VHH L-P2-B10, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | inhibitor, complex, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 171064.11 |
Authors | Gros, P.,van Scherpenzeel, R.C. (deposition date: 2018-07-11, release date: 2019-01-30, Last modification date: 2024-01-17) |
Primary citation | Fenderico, N.,van Scherpenzeel, R.C.,Goldflam, M.,Proverbio, D.,Jordens, I.,Kralj, T.,Stryeck, S.,Bass, T.Z.,Hermans, G.,Ullman, C.,Aastrup, T.,Gros, P.,Maurice, M.M. Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells. Nat Commun, 10:365-365, 2019 Cited by PubMed: 30664649DOI: 10.1038/s41467-018-08172-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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