6H15
Structure of LRP6 P3E3P4E4 in complex with VHH L-P2-B10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | Low-density lipoprotein receptor-related protein 6 | polymer | 616 | 69738.5 | 2 | UniProt (O75581) Pfam (PF00058) Pfam (PF14670) | Homo sapiens (Human) | LRP-6 |
| 2 | B, C (C, D) | VHH L-P2-B10 | polymer | 123 | 13731.1 | 2 | Lama glama (Llama) | ||
| 3 | E, G (E, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | F, I (F, I) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 5 | H (H) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 6 | J, K, L, Q, R (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 7 | M, N, O, P, S... (A, C, B) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 8 | V, W, X, Y (A, C, D, B) | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence modifications
A, B: 630 - 1244 (UniProt: O75581)
| PDB | External Database | Details |
|---|---|---|
| Ala 1245 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 166939.3 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2770.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1354.2 | |
| All* | Total formula weight | 171064.1 |
