6GOM
KRAS-169 Q61H GPPNHP + PPIN-1
Summary for 6GOM
Entry DOI | 10.2210/pdb6gom/pdb |
Related | 6GOD 6GOE 6GOF 6GOG |
Descriptor | GTPase KRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | kras, oncoprotein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 6 |
Total formula weight | 121799.04 |
Authors | Cruz-Migoni, A.,Canning, P.,Quevedo, C.E.,Carr, S.B.,Phillips, S.E.V.,Rabbitts, T.H. (deposition date: 2018-06-01, release date: 2019-02-06, Last modification date: 2024-01-17) |
Primary citation | Cruz-Migoni, A.,Canning, P.,Quevedo, C.E.,Bataille, C.J.R.,Bery, N.,Miller, A.,Russell, A.J.,Phillips, S.E.V.,Carr, S.B.,Rabbitts, T.H. Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds. Proc. Natl. Acad. Sci. U.S.A., 116:2545-2550, 2019 Cited by PubMed: 30683716DOI: 10.1073/pnas.1811360116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
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