6GKV
Crystal structure of Coclaurine N-Methyltransferase (CNMT) bound to N-methylheliamine and SAH
Summary for 6GKV
Entry DOI | 10.2210/pdb6gkv/pdb |
Descriptor | Coclaurine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium, ... (4 entities in total) |
Functional Keywords | n-methylheliamine, coclaurine n-methyltransferase, transferase |
Biological source | Coptis japonica (Japanese goldthread) |
Total number of polymer chains | 2 |
Total formula weight | 83326.99 |
Authors | Dunstan, M.S.,Levy, C.W. (deposition date: 2018-05-22, release date: 2018-06-06, Last modification date: 2024-05-15) |
Primary citation | Bennett, M.R.,Thompson, M.L.,Shepherd, S.A.,Dunstan, M.S.,Herbert, A.J.,Smith, D.R.M.,Cronin, V.A.,Menon, B.R.K.,Levy, C.,Micklefield, J. Structure and Biocatalytic Scope of Coclaurine N-Methyltransferase. Angew. Chem. Int. Ed. Engl., 57:10600-10604, 2018 Cited by PubMed: 29791083DOI: 10.1002/anie.201805060 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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