6G6X
14-3-3sigma in complex with a P129beta3P mutated YAP pS127 phosphopeptide
Summary for 6G6X
Entry DOI | 10.2210/pdb6g6x/pdb |
Descriptor | 14-3-3 protein sigma, Transcriptional coactivator YAP1, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | beta amino acid hippo pathway yap/taz, oncoprotein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 27905.90 |
Authors | Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. (deposition date: 2018-04-03, release date: 2019-04-10, Last modification date: 2024-01-17) |
Primary citation | Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. A study on the effect of synthetic alpha-to-beta3-amino acid mutations on the binding of phosphopeptides to 14-3-3 proteins. Chem.Commun.(Camb.), 55:14809-14812, 2019 Cited by PubMed: 31763628DOI: 10.1039/c9cc07982c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.13 Å) |
Structure validation
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