6G6X

14-3-3sigma in complex with a P129beta3P mutated YAP pS127 phosphopeptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	14-3-3 protein sigma	polymer	236	26542.9	1	UniProt (P31947) Pfam (PF00244) In PDB	Homo sapiens (Human)	Epithelial cell marker protein 1,Stratifin
2	P	Transcriptional coactivator YAP1	polymer	11	1175.2	1	UniProt (P46937) In PDB	Homo sapiens	Yes-associated protein 1,Protein yorkie homolog,Yes-associated protein YAP65 homolog
3	A	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
4	A	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5		water	water		18.0	399	Chemie (HOH)

Sequence modifications

A: 1 - 231 (UniProt: P31947)

PDB	External Database	Details
Gly -4	-	expression tag
Ala -3	-	expression tag
Met -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

P: 124 - 133 (UniProt: P46937)

PDB	External Database	Details
Ace 123	-	expression tag
Eoe 129	Pro 129	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27718.1
Non-Polymers*	Number of molecules	6
	Total formula weight	187.8
All*	Total formula weight	27905.9

*Water molecules are not included.