6G6X
14-3-3sigma in complex with a P129beta3P mutated YAP pS127 phosphopeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (P) | Transcriptional coactivator YAP1 | polymer | 11 | 1175.2 | 1 | UniProt (P46937) | Homo sapiens | Yes-associated protein 1,Protein yorkie homolog,Yes-associated protein YAP65 homolog |
| 3 | C, D, E, F (A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | G, H (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | I, J (A, P) | water | water | 18.0 | 399 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
P: 124 - 133 (UniProt: P46937)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 123 | - | expression tag |
| Eoe 129 | Pro 129 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27718.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 187.8 | |
| All* | Total formula weight | 27905.9 |
