6G46
Red kidney bean purple acid phosphatase in complex with 2-(Naphthalen-1-yl)thiazole-4-carboxylic acid
Summary for 6G46
Entry DOI | 10.2210/pdb6g46/pdb |
Descriptor | Fe(3+)-Zn(2+) purple acid phosphatase, SODIUM ION, ISOPROPYL ALCOHOL, ... (13 entities in total) |
Functional Keywords | phosphatase, metallohydrolase, hydrolase, metalloprotein, purple acid phosphatase, pap, red kidney bean, rkbpap, drug design, drug discovery, rational drug design, osteoporosis, metal binding protein |
Biological source | Phaseolus vulgaris (Kidney bean) |
Total number of polymer chains | 4 |
Total formula weight | 206715.09 |
Authors | Feder, D.F. (deposition date: 2018-03-26, release date: 2018-09-26, Last modification date: 2024-01-17) |
Primary citation | Hussein, W.M.,Feder, D.,Schenk, G.,Guddat, L.W.,McGeary, R.P. Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics. Eur J Med Chem, 157:462-479, 2018 Cited by PubMed: 30107365DOI: 10.1016/j.ejmech.2018.08.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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